University of Pittsburgh researchers have shown for the first time how Merkel cell polyomavirus (MCV), which causes an aggressive skin cancer called Merkel cell carcinoma, initiates DNA replication in host cells. Published today in the journal PNAS , the study sheds light on the fundamental question of how viruses override their host cells' carefully regulated DNA replicating system to make hundreds of new copies of themselves. "Understanding how MCV replicates gives us really important clues about how this virus can cause cancer," said co-senior author Patrick Moore, M.

https://www.miragenews.com/skin-cancer-virus-outcompetes-host-cell-1048306/

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