A study published Oct. 4 in Gastroenterology further validates that pyrvinium, a drug that has been used for decades for intestinal pinworms, can be repurposed as a preventative treatment for stomach cancer. Eunyoung Choi, PhD Eunyoung Choi, PhD, assistant professor of Surgery, and colleagues have demonstrated in human organoids and mouse models that the drug induces cell death in precancerous lesions. Pyrvinium blockades both the MEK/ERK and STAT3 signaling pathways. In another study she led, which was published last year in Gastroenterology , the researchers demonstrated that pyrvinium blocked regeneration of dysplastic stem cells.

https://www.miragenews.com/research-confirms-pyrvinium-as-stomach-cancer-1098450/

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