Key Takeaways Analyses of atrial heart tissue collected from patients with and without atrial fibrillation indicate that immune cells called macrophages expand more than any other cell type in diseased tissue. In a mouse model of atrial fibrillation, macrophages support inflammation and scarring of the atria, which hinder electrical conduction between heart cells. The SPP1 gene is highly overexpressed in macrophages during atrial fibrillation, and its expressed protein promotes tissue scarring. BOSTON – Current treatments for atrial fibrillation (AFib), a common heart condition characterized by fast and irregular beats that can lead to stroke and heart failure, have multiple side effects and are ineffective for preventing AFib recurrence.

https://www.miragenews.com/targeting-immune-cells-may-aid-atrial-1046635/

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