SAN CARLOS, California – Integrated Biosciences, a biotechnology company combining synthetic biology and machine learning to target aging, in collaboration with researchers at the University of California Santa Barbara, today announced a drug discovery platform that enables precise control of the integrated stress response (ISR), a biological pathway that is activated by cells in response to a wide variety of pathological and aging-associated conditions. A new publication, " Optogenetic control of the integrated stress response reveals proportional encoding and the stress memory landscape ," authored by company founders and featured on the cover of Cell Systems describes a technique that triggers the ISR virtually using light and demonstrates how the accumulation of stress over time shifts a cell's reaction from adaptation to apoptosis (programmed cell death).

https://www.miragenews.com/integrated-biosciences-unveils-breakthrough-1050014/

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