Proteins called transcription factors are like molecular traffic cops that tell genes when to stop and go. If they malfunction - what scientists refer to as dysregulation - transcription factors stop orchestrating healthy gene expression and instead become a driving force for diseases like cancer. Unsurprisingly, dysregulated transcription factors have garnered a lot of attention from researchers hoping to create new treatments for disease. But transcription factors have proven hard to drug, in part because they work in the context of various interdependent signaling molecules in the cell.
https://www.miragenews.com/studying-cancer-in-context-to-stop-its-growth-1094946/#miragenews
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