Researchers at the Johns Hopkins University School of Medicine have developed a mouse model that successfully mimics the development of frailty as mammals - likely including people - get older. The model, described June 13 in The Journals of Gerontology , focuses on a biochemical pathway involving interleukin 6 (IL-6), an inflammatory protein long associated with the development of frailty, and how its activation affects mitochondria, the power plants of cells. "Frailty is a syndrome characterized by reduced strength, energy and activity, as well as lowered physical resilience among older adults," says Peter Abadir, M.

https://www.miragenews.com/inflammatory-biomarker-tied-to-mitochondrial-1044736/

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