Nitric oxide (NO) is a fascinating and versatile molecule, important for all living things as well as the environment. It is highly reactive and toxic, organisms use it as a signaling molecule, it depletes the ozone layer in our planet's atmosphere, and it is the precursor of the greenhouse gas nitrous oxide (N 2 O). Moreover, NO might have played a fundamental role in the emergence and evolution of life on Earth, as it was available as a high-energy oxidant long before there was oxygen. Thus, despite its toxicity, it makes perfect sense that microbes use NO to grow.

https://www.miragenews.com/breathing-poison-microbial-life-on-nitric-oxide-1043914/

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